I have prayed the Memorare every day since my mom (and others) told me to go to Mary with my depression. It’s clear from the words of this prayer that Mary hears all pleas, but especially those uttered in desperation:

“Remember O Most gracious Virgin Mary, that never was it known that anyone who fled to your protection, implored your help, or sought your intercession was left unaided. Inspired by this confidence, I fly to you, O Virgin of virgins, my mother. To you I come; before you I stand, sinful and sorrowful. O Mother of the Word Incarnate, despise not my petitions, but in your mercy, hear and answer me. Amen.”