Our people are being shot by guns manufactured in Iran and Powell wants to talk to them. He thinks they can play a “responsible part in the region.” This type of thinking went out with Neville Chamberlain:

Powell wants to Former U.S. Secretary of State Colin Powell does not believe the United States will attack Iran and says Washington should speak to Tehran and Syria.
Powell, who said Iraq was in a civil war on Wednesday, was speaking to the Leaders in London Business Forum on Thursday.
Answering a question from Reuters, Powell said: “Iran is a regional power and it will have to be dealt with. We should find ways to speak to them and also speak to the Syrians.”
Both Iran and Syria have been accused by the U.S. government of sponsoring terrorism and fomenting violence in Iraq. Iran has also been accused of trying to build nuclear weapons. Both countries deny the accusations.
“I hope that over time Iran will play a responsible part in the region,” he said. “As you know Iran is doing very well now, they have no particular pressure on their nuclear program.”

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If you think that the leader of Iran is “responsible” you might want to note the words at the end of his letter to the American people:

The US governing establishment, the authorities and the powerful should not choose irreversible paths. As all prophets have taught us, injustice and transgression will eventually bring about decline and demise. Today, the path of return to faith and spirituality is open and unimpeded.
We should all heed the Divine Word of the Holy Qur’an:
“But those who repent, have faith and do good may receive Salvation. Your Lord, alone, creates and chooses as He will, and others have no part in His choice; Glorified is God and Exalted above any partners they ascribe to Him.” (28:67-68)
What faith do you think he’s referring to there? He’s telling the American people to repent or face the consequences. Powell, are you ready to convert to Islam? If not, then why negotiate?