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Luke wrote one of the major portions of the New Testament, a two-volume work comprising the third Gospel and the Acts of the Apostles. In the two books he shows the parallel between the life of Christ and that of the Church. He is the only Gentile Christian among the Gospel writers. Tradition holds him to be a native of Antioch, and Paul calls him "our beloved physician" (Colossians 4:14). His Gospel was probably written between A.D. 70 and 85.

Luke appears in Acts during Paul’s second journey, remains at Philippi for several years until Paul returns from his third journey, accompanies Paul to Jerusalem and remains near him when he is imprisoned in Caesarea. During these two years, Luke had time to seek information and interview persons who had known Jesus. He accompanied Paul on the dangerous journey to Rome where he was a faithful companion. "Only Luke is with me," Paul writes (2 Timothy 4:11).